将熔融法制备的硼酸盐生物玻璃按不同比率与羟基磷灰石混合烧结,制备出双相材料支架样品.将各组样品浸泡在生理模拟液中(5 g样品/100 mL浸泡液),置于37℃恒温条件下,进行体外生物矿化反应,考察了支架的降解性能随羟基磷灰石含量的变化情况.实验中,通过ICP测试,研究了硼元素在支架降解过程中的释放情况.通过XRD和FTIR分析了产生变化的原因,结果表明硼酸盐生物活性玻璃与羟基磷灰石在600℃混合烧结后会产生新的晶相,使得结构更加稳定,降解速度放缓,尤其克服了B元素在降解初期的过量释放.
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