The purpose of this study was to find a kind of new artificial bone for anterior spinal fusion.ZrO2 stabilized by Y2O3 ( Y- PSZ), porous hydroxyapatite ( HA ) and bone morphogenetic protein (BMP) were used to make artificial compound bone ( Y2O3 ) ZrO2 -HA/ BMP( Z-H/ BMP ) , whose function was tested, microstructure and mineralogic composition constitution were analysised by SEM and XRD , and the corresponding animal tests were porformed. Osteogenesis of the material was observed by eyes, histology and SEM. Experimental results show that the component and ossific activity of Z-H/BMP were satisfactory.
参考文献
| [1] | Takahata M;Kotani Y;Abumi K;Shikinami Y;Kadosawa T;Kaneda K;Minami A .Bone ingrowth fixation of artificial intervertebral disc consisting of bioceramic-coated three-dimensional fabric.[J].Spine,2003(7):637-644. |
| [2] | Thalgott JS;Fritts K;Giuffre JM;Timlin M .Anterior interbody fusion of the cervical spine with coralline hydroxyapatite.[J].Spine,1999(13):1295-1299. |
| [3] | Kasai Y;Takegami K;Uchida A .Mixture ratios of local bone to artificial bone in lumbar posterolateral fusion.[J].Journal of spinal disorders & techniques,2003(1):31-37. |
| [4] | Ohnishi T;Neo M;Matsushita M et al.Delayed Aortic Rupture Caused by an Implanted Anterior Spinal Device[J].Journal of Neurosurgery,2001,95:253-256. |
| [5] | Li Yafei;Hu Yunyu;Li Xuebing et al.Influence of Geometry of Bone Particals and Intensely Stirring of the Extraction on the Yield of bBMP and its Osteoinductivity[J].Chinese Journal of Orthopedics,1996,16(02):118-120. |
| [6] | DAI Hong-lian,Cao Xian-ying,LI Xiao-xi,YAN Yu-hua,LI Shi-pu.The Transformation of Calcium Phosphate Bioceramics in Vivo[J].武汉理工大学学报(材料科学版)英,2003(02):19-22. |
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