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水凝胶是在水中溶胀并保持大量水分而又不溶解的聚合物,与生物机体组织很相似.蛋白基水凝胶具有良好的生物相容性和生物降解性,在组织工程中的应用主要是恢复、维持或改善受损机体组织与器官的形态和功能,以达到修复再生的目的,被誉为下一代最具潜力的组织工程用生物材料.综述了组织工程用天然蛋白基和合成蛋白基水凝胶的研究进展,并指出了其优、缺点及发展方向.

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