以聚四氢呋喃醚（PTMG）二醇和甲苯二异氰酸酯（TDI）为原料，2-羟甲基丙酸（DMPA）为亲水扩链剂，通过自乳化方法初步合成了聚氨酯乳液。将乳液成膜，通过红外、热重、透射电镜、力学测试等对材料的化学组成与微观结构进行表征，进一步通过体外细胞实验对材料与细胞的相互作用进行评价。结果表明制备的水性聚氨酯乳液粒径均匀，热稳定性良好，具有一定的形状记忆功能，对细胞无毒性，相容性好，对细胞的生长繁殖几乎无影响，是一种具有广阔应用前景的生物材料。
Based on polyether （PTMG1000）, toluene-diisoeyanate （TDI） and dimethoxy acid （DMPA）, a water- borne polyurethane emulsion was synthesized by self-emulsion method. The structure and properties of the sam- ple were investigated by ATR-IR, TG, TEM and mechanical test. The results revealed that urea linkage was formed by the reaction of isocyanates with hydroxyl; the samples synthesized had high thermal stability and a uniform distribution of particle size was achieved in waterbone polyurethane emulsion. It was also found that the waterborne polyurethane had a good shape memory function. Its cytotoxicity was also tested and the result showed that it had good cytocompatibiiity.
参考文献
| [1] | Bos G W;PootA A;Beugeling et al.[J].Archives Physiology Biochemistry,1998,106(02):100-115. |
| [2] | 潘仕荣,杨世方,易武,郑欢玲,陶军.小径微孔聚氨酯人工血管的制备条件对微观结构与性能的影响[J].中国修复重建外科杂志,2005(01):64-69. |
| [3] | 李军;龚志超;邓联东 等.[J].化学工业与工程,2001,21(04):235-238. |
| [4] | 郑玉峰;李莉.生物医用材料学[M].哈尔滨:哈尔滨工业大学出版社,2005:241. |
| [5] | Anderson J M;Hiltner R A;Wiggins M J et al.[J].Polymer International,1998,46(03):163-171. |
| [6] | 孔桦,许海燕,蔺嫦燕,李冰一.纳米碳改性聚氨酯复合材料的表面抗凝血性能[J].基础医学与临床,2002(02):113-116. |
| [7] | Luo Ning;Wang Dening;Ying Shengkang .[J].Macromolecules,1997,30:4405-4409. |
| [8] | 游晓亮,夏修旸 |
| [9] | Zhu Xiaoili;Jiang Xubao;Zhang Zhiguo et al.[J].Progress in Organic Coatings,2008,62:251-257. |
| [10] | Takahashi T.;Hayashi S.;Hayashi N. .STRUCTURE AND PROPERTIES OF SHAPE-MEMORY POLYURETHANE BLOCK COPOLYMERS[J].Journal of Applied Polymer Science,1996(7):1061-1069. |
| [11] | 吴嘉民,姜志国,赵春玉,周亨近.硬段含量对热致形状记忆聚氨酯材料记忆性能的影响[J].北京化工大学学报(自然科学版),2003(01):89-91. |
| [12] | Du Renguo .[J].Journal of Functional Materials,1995,26(02):107112. |
| [13] | 左兰,陈大俊.形状记忆聚氨酯的研究与应用[J].弹性体,2002(06):56-60. |
- 下载量()
- 访问量()
- 您的评分：
-
10%
-
20%
-
30%
-
40%
-
50%