{"currentpage":1,"firstResult":0,"maxresult":10,"pagecode":5,"pageindex":{"endPagecode":5,"startPagecode":1},"records":[{"abstractinfo":"在碘化亚铜、四丁基溴化铵和磷酸钾存在下,9,9-<span style=\"color:red\">二</span>(4-羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>(1)和4-甲基碘<span style=\"color:red\">苯</span>(2)于N,N-<span style=\"color:red\">二</span>甲基甲酰胺溶剂中发生Ullmann偶联反应,加热回流反应24 h,以95%的产率合成了中间体--9,9-<span style=\"color:red\">二</span>[4-(4-甲基<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">苯基</span>]<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>(3),继而加入催化量的N-溴代丁<span style=\"color:red\">二</span>酰亚胺并在光照条件下,将中间体3氧化得到一种新型芳香族<span style=\"color:red\">二</span>羧酸--9,9-<span style=\"color:red\">二</span>[4-(4-<span style=\"color:red\">羧基</span><span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">苯基</span>]<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>(4),其产率为84%,<span style=\"color:red\">二</span>步反应总收率为79.8%. 目标化合物4经1H NMR、13C NMR、IR和元素分析测试技术确定了其结构. 该法具有原料易得,操作简单,反应条件温和,收率高等优点.","authors":[{"authorName":"付桂云","id":"d1f14824-c831-47a3-bbc4-afaa64ac52b9","originalAuthorName":"付桂云"},{"authorName":"魏梅红","id":"3cd687c2-160b-4e63-b050-63616df6372a","originalAuthorName":"魏梅红"},{"authorName":"盛寿日","id":"59194085-2e5e-4da3-9b29-6a9cf3c9face","originalAuthorName":"盛寿日"},{"authorName":"姜建文","id":"543cf648-233c-4d28-a779-60174588be98","originalAuthorName":"姜建文"}],"doi":"10.3724/SP.J.1095.2010.00059","fpage":"1478","id":"aad98c3a-7759-45cb-9444-9a46e76279b0","issue":"12","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"9a0ff258-4cb2-4043-bdc4-3acd249a2904","keyword":"<span style=\"color:red\">二</span>[(<span style=\"color:red\">羧基</span><span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">苯基</span>]<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>","originalKeyword":"二[(羧基苯氧基)苯基]呫吨"},{"id":"d4b9adb3-2660-4349-b79e-009d152b92c6","keyword":"<span style=\"color:red\">二</span>(羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>","originalKeyword":"二(羟基苯基)呫吨"},{"id":"8ce10ae8-4c2e-404e-a54f-f8c9257416ac","keyword":"甲基碘<span style=\"color:red\">苯</span>","originalKeyword":"甲基碘苯"},{"id":"dd287a3e-dd9f-4c66-96b3-6848b1350433","keyword":"Ullmann反应","originalKeyword":"Ullmann反应"},{"id":"60e3f6f6-8408-4896-bc77-6defa55ac25e","keyword":"氧化反应","originalKeyword":"氧化反应"}],"language":"zh","publisherId":"yyhx201012023","title":"9,9-<span style=\"color:red\">二</span>[4-(4-<span style=\"color:red\">羧基</span><span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">苯基</span>]<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>的合成","volume":"27","year":"2010"},{"abstractinfo":"以醋酸酐为溶剂,将9,9-<span style=\"color:red\">二</span>(4-羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>与浓硝酸在15℃左右发生硝化反应1.5h,形成中间体-9,9-<span style=\"color:red\">二</span>(3-硝基-4-羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>,产率为88.5％;继而以Pd/C为催化剂,80％的水合肼为还原剂,在乙醇和1,4-<span style=\"color:red\">二</span>.氧六环混合溶剂中,于70℃将中间体进行还原反应10 h,得到目标产物9,9-<span style=\"color:red\">二</span>(3-氨基-4-羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>,产率为90.8％,两步反应总收率为80.4％.中间体与目标化合物经NMR、FTIR和元素分析等确定了它们的结构.","authors":[{"authorName":"方程","id":"80079bc3-e803-41f2-8716-97884536645a","originalAuthorName":"方程"},{"authorName":"姜建文","id":"152c00f7-4093-4801-ac8a-670519077602","originalAuthorName":"姜建文"},{"authorName":"刘晓玲","id":"591766f0-b3b6-4260-bcd9-5c331d6d5895","originalAuthorName":"刘晓玲"},{"authorName":"盛寿日","id":"1405ab25-3661-48fd-ba02-54272f167f55","originalAuthorName":"盛寿日"}],"doi":"10.11944/j.issn.1000-0518.2015.01.140123","fpage":"60","id":"6b7acbbf-5f31-4be8-8d68-aa365501347c","issue":"1","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"00e699c7-c058-4ec3-bed8-31223d3c9876","keyword":"<span style=\"color:red\">二</span>(硝基羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>","originalKeyword":"二(硝基羟基苯基)呫吨"},{"id":"faa2f4ed-5fb1-4ebd-970c-5335b8a5b62d","keyword":"<span style=\"color:red\">二</span>(氨基羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>","originalKeyword":"二(氨基羟基苯基)呫吨"},{"id":"c5e15369-3cc9-4459-9ff7-298426aacfba","keyword":"硝化反应","originalKeyword":"硝化反应"},{"id":"c8961650-3a0f-44d2-a135-2d63c5f80b59","keyword":"还原反应","originalKeyword":"还原反应"},{"id":"85515e62-5f66-4278-b455-381d0fb8fb51","keyword":"水合肼","originalKeyword":"水合肼"}],"language":"zh","publisherId":"yyhx201501008","title":"9,9-<span style=\"color:red\">二</span>(3-氨基-4-羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>的合成","volume":"32","year":"2015"},{"abstractinfo":"由9,9-<span style=\"color:red\">二</span>(4-羟基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>和对氟硝基<span style=\"color:red\">苯</span>反应制得<span style=\"color:red\">二</span>硝基化合物,继而用水合肼/钯碳将其还原得到<span style=\"color:red\">二</span>胺-9,9-<span style=\"color:red\">二</span>(4-氨基<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span><span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>(BAPX).采用Yamazaki聚合体系,将BAPX与1,4(或2,6)-萘<span style=\"color:red\">二</span>酸进行缩聚合成了两种新型含<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>和萘环结构的聚酰胺,<span style=\"color:red\">二</span>者均为无定型结构,英特性黏度、玻璃化转变温度(Tg)分别为0.98 dL/g和1.0dL/g、295℃和302℃.在氮气和空气气氛中,10%的热失重温度(Td10)均在505℃以上,在氮气中,800℃时的残炭率大于65%;在常温下易溶于N-甲基-2-吡咯烷酮(NMP)、N,N-<span style=\"color:red\">二</span>甲基乙酰胺(DMAc)和间甲酚等极性溶剂中,可通过溶液浇铸成透明、韧性的薄膜,膜的拉伸强度、断裂伸长率和杨氏模量依次分别为105 Mpa和110 Mpa、13.1%和13.3%、2.88 Gpa和3.05 Gpa.","authors":[{"authorName":"姜建文","id":"09ac18a0-be80-4494-8241-8398a93207f2","originalAuthorName":"姜建文"},{"authorName":"万雪梅","id":"62d99b63-3c79-4d53-bb4d-be7e82e3b22b","originalAuthorName":"万雪梅"},{"authorName":"盛寿日","id":"7e5c9647-15d3-4b6b-bcb2-1fa86fa75a8e","originalAuthorName":"盛寿日"},{"authorName":"陈诚","id":"ece9829b-872c-44b0-baf3-ab21efaf10bf","originalAuthorName":"陈诚"},{"authorName":"黄振中","id":"8ce8b7ca-cece-41d9-b252-cefe2beb509a","originalAuthorName":"黄振中"},{"authorName":"宋才生","id":"a5237ee4-6b84-477d-96b3-263df27019d3","originalAuthorName":"宋才生"}],"doi":"","fpage":"31","id":"c5fb13d9-a89a-4113-b7e6-3fdaf59ce8c5","issue":"12","journal":{"abbrevTitle":"GFZCLKXYGC","coverImgSrc":"journal/img/cover/GFZCLKXYGC.jpg","id":"31","issnPpub":"1000-7555","publisherId":"GFZCLKXYGC","title":"高分子材料科学与工程"},"keywords":[{"id":"ba75b125-a86c-433d-9a63-d8e494bc06e8","keyword":"聚酰胺","originalKeyword":"聚酰胺"},{"id":"494c8785-cf70-4e48-b301-c7343450b219","keyword":"cardo型结构","originalKeyword":"cardo型结构"},{"id":"9e5a1b81-2b15-4bd8-a048-73387ec372c9","keyword":"9,9-<span style=\"color:red\">二</span>(4-胺基<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span><span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>","originalKeyword":"9,9-二(4-胺基苯氧基苯基)呫吨"},{"id":"b9b23470-b3b1-4a6f-89cd-bd231744bd3b","keyword":"萘<span style=\"color:red\">二</span>酸","originalKeyword":"萘二酸"},{"id":"26a9b87f-509c-4e86-9abb-44920adf5a95","keyword":"可溶性","originalKeyword":"可溶性"}],"language":"zh","publisherId":"gfzclkxygc201012009","title":"一种含<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>和萘环结构的可溶性聚酰胺的合成与性能","volume":"26","year":"2010"},{"abstractinfo":"以DMF作溶剂,在四丁基氟化铵 (TBAF)存在下,对甲基<span style=\"color:red\">苯基</span>三甲硅基醚(1)和4,4'-<span style=\"color:red\">二</span>氯<span style=\"color:red\">二</span><span style=\"color:red\">苯</span>砜(2)于100 ℃反应1 h,合成了4,4'-<span style=\"color:red\">二</span>(4-甲基<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">二</span><span style=\"color:red\">苯</span>砜(3),产率为92%;加入催化量的N-溴代丁<span style=\"color:red\">二</span>酰亚胺(NBS)并在光照条件下,与氧气反应得到中间体-4,4'-<span style=\"color:red\">二</span>(4-<span style=\"color:red\">羧基</span><span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">二</span><span style=\"color:red\">苯</span>砜(4),其产率达90%;将化合物4与<span style=\"color:red\">二</span>氯亚砜反应合成目标产物4,4'-<span style=\"color:red\">二</span>(4-氯甲酰基<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">二</span><span style=\"color:red\">苯</span>砜(5),总收率为74.5%(以对甲基<span style=\"color:red\">苯基</span>三甲硅基醚为基准计算).","authors":[{"authorName":"黄振钟","id":"2b35d8a7-0015-4415-abc4-44d1cb58d824","originalAuthorName":"黄振钟"},{"authorName":"霍毅","id":"3db00dca-4aca-4f07-a3a3-45bf0b000129","originalAuthorName":"霍毅"},{"authorName":"罗秋燕","id":"9aebb808-e8c0-4b0a-abf0-c1b0be35bb7e","originalAuthorName":"罗秋燕"},{"authorName":"刘卓","id":"b756e243-dc43-4659-8843-452946312584","originalAuthorName":"刘卓"},{"authorName":"盛寿日","id":"1580cc88-d9c5-4bbb-8fbd-e36797a992dc","originalAuthorName":"盛寿日"}],"doi":"10.3969/j.issn.1000-0518.2007.08.013","fpage":"917","id":"ea9c6c7f-4283-4583-b7b0-b2b4bdcbaf39","issue":"8","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"b4803760-369e-4c20-9f98-0f6a6bc3fc58","keyword":"对甲基<span style=\"color:red\">苯基</span>三甲硅基醚","originalKeyword":"对甲基苯基三甲硅基醚"},{"id":"287fc71e-97d1-4124-841e-a7b3396c0c22","keyword":"<span style=\"color:red\">二</span>氯<span style=\"color:red\">二</span><span style=\"color:red\">苯</span>砜","originalKeyword":"二氯二苯砜"},{"id":"8e5e150d-e3ac-4338-a550-17ead5aac7b0","keyword":"<span style=\"color:red\">二</span>(氯甲酰基<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">二</span><span style=\"color:red\">苯</span>砜","originalKeyword":"二(氯甲酰基苯氧基)二苯砜"},{"id":"ddd952a9-bf50-4dc0-92a1-241cd2e5b990","keyword":"合成","originalKeyword":"合成"}],"language":"zh","publisherId":"yyhx200708013","title":"4,4'-<span style=\"color:red\">二</span>(4-氯甲酰<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>)<span style=\"color:red\">二</span><span style=\"color:red\">苯</span>砜的合成","volume":"24","year":"2007"},{"abstractinfo":"合成了一种耐高温的3,4-<span style=\"color:red\">二</span>(3-<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>-4-氟<span style=\"color:red\">苯基</span>)-2,5-<span style=\"color:red\">二</span><span style=\"color:red\">苯基</span><span style=\"color:red\">苯基</span>接枝聚硅氧烷(DPFP)固定相,使用静态涂渍法将其涂渍到毛细管柱内壁上,制成气相色谱柱.分离裂解乙烯的色谱图显示DPFP固定相在360 ℃时仍具有良好的分离能力.DPFP固定相的柱效为3324块/米(保留因子(k)4.24,萘,0.25 mm i.d.).麦克雷诺常数计算结果显示DPFP固定相属中等极性.溶剂化参数模型结果显示DPFP固定相与溶质之间的主要作用力为偶极-诱导偶极作用力、氢键碱性作用力.Grob试剂分离结果显示DPFP色谱柱具有良好的选择性与惰性.另外,芳香族同分异构体、<span style=\"color:red\">苯</span>取代物、多环芳烃、脂肪酸酯及脂肪醇都得到了良好的分离,表明DPFP固定相在应用方面有巨大的潜力.","authors":[{"authorName":"王欢","id":"5e47df93-6c20-40aa-8ac9-b0a03b310d5b","originalAuthorName":"王欢"},{"authorName":"韩雪","id":"8a2e4545-2aa4-4f89-8fb1-66ba7d622b96","originalAuthorName":"韩雪"},{"authorName":"贺新新","id":"0ebb067f-79bf-4a3d-b6cb-068f23385152","originalAuthorName":"贺新新"},{"authorName":"王冰","id":"b0e54c4c-51a3-4bc8-bc55-5354e6d8b0d5","originalAuthorName":"王冰"},{"authorName":"吴波","id":"8cb27814-5cd0-458e-90e0-bb4b2cbcc542","originalAuthorName":"吴波"}],"doi":"10.3724/SP.J.1123.2016.07026","fpage":"388","id":"404c89eb-c10c-4855-be25-6fc8f664d864","issue":"4","journal":{"abbrevTitle":"SP","coverImgSrc":"journal/img/cover/SP.jpg","id":"58","issnPpub":"1000-8713","publisherId":"SP","title":"色谱 "},"keywords":[{"id":"3f616924-400d-4baf-94d1-d58360513891","keyword":"聚硅氧烷","originalKeyword":"聚硅氧烷"},{"id":"b9e50d1e-f197-453c-81af-1f6b0cc173c4","keyword":"气相色谱","originalKeyword":"气相色谱"},{"id":"0b46d11a-c67d-440c-bd7a-dbd1ef39b1ee","keyword":"固定相","originalKeyword":"固定相"},{"id":"15a4cbe6-14ae-4243-9c5a-a5335e7b7862","keyword":"耐温性","originalKeyword":"耐温性"},{"id":"13b6ac95-41b7-478c-9747-169bb5393dbc","keyword":"选择性","originalKeyword":"选择性"}],"language":"zh","publisherId":"sp201704005","title":"3,4-<span style=\"color:red\">二</span>(3-<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>-4-氟<span style=\"color:red\">苯基</span>)-2,5-<span style=\"color:red\">二</span><span style=\"color:red\">苯基</span><span style=\"color:red\">苯基</span>接枝聚硅氧烷气相色谱固定相的合成与表征","volume":"35","year":"2017"},{"abstractinfo":"采用两步法合成了六对<span style=\"color:red\">羧基</span><span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>环三磷腈(HCPCP). 以六氯环三磷腈和对羟基<span style=\"color:red\">苯</span>甲醛为原料,利用亲核取代反应制得六对醛基<span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>环三磷腈(HAPCP),再用KMnO4氧化法合成HCPCP. 通过红外光谱仪、高效液相色谱仪、核磁共振仪及元素分析确证了产物的结构;用TGA和DSC测试技术对其热性能进行分析. 结果表明,HCPCP对ABS树脂有良好的阻燃作用,添加量30%时,阻燃ABS树脂氧指数提高至25%.","authors":[{"authorName":"邴柏春","id":"676babe9-4e74-4e21-a33b-017090159bb5","originalAuthorName":"邴柏春"},{"authorName":"李斌","id":"b800902e-d1be-4ca4-ba30-5eba5f309d72","originalAuthorName":"李斌"},{"authorName":"贾贺","id":"407261af-8eb4-4726-bbe8-495ca405aeb2","originalAuthorName":"贾贺"},{"authorName":"杨明非","id":"97025660-162b-418b-bb34-eb07267fcc8a","originalAuthorName":"杨明非"}],"doi":"10.3969/j.issn.1000-0518.2009.07.002","fpage":"753","id":"459df748-f552-49a7-962e-868eb9e314a6","issue":"7","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"a0445214-a0ea-43e6-87de-18a034dd103f","keyword":"六氯环三磷腈","originalKeyword":"六氯环三磷腈"},{"id":"a4b19a36-b796-4486-99a3-9546f2c7c7ed","keyword":"六对<span style=\"color:red\">羧基</span><span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>环三磷腈","originalKeyword":"六对羧基苯氧基环三磷腈"},{"id":"7ea8c2be-79f3-460d-9588-34b58bd896b3","keyword":"合成","originalKeyword":"合成"},{"id":"afd1c6af-3b6d-4dab-adc8-1190450c05f1","keyword":"热性能","originalKeyword":"热性能"}],"language":"zh","publisherId":"yyhx200907002","title":"六对<span style=\"color:red\">羧基</span><span style=\"color:red\">苯</span><span style=\"color:red\">氧基</span>环三磷腈的合成及其热性能","volume":"26","year":"2009"},{"abstractinfo":"4-烷<span style=\"color:red\">氧基</span>联苯-4′-甲酸-(4-<span style=\"color:red\">羧基</span>)<span style=\"color:red\">苯</span>酯是许多铁电液晶、反铁电液晶的中间体。从联苯酚出发经甲基化、乙酰化、卤仿反应、脱甲基化、烷基化、缩合、还原等多步反应合成了一系列此类液晶中间体，其中多数经过IR， 1H NMR和MS谱图检测，确定了其分子结构。","authors":[{"authorName":"窦清玉","id":"bded3fc1-4466-4b50-9b16-590708540791","originalAuthorName":"窦清玉"},{"authorName":"高建宝","id":"5626cabf-c51a-4554-981b-2029e643858b","originalAuthorName":"高建宝"},{"authorName":"奚关根","id":"f9de5234-5771-4eff-918c-bfbe24ff62a7","originalAuthorName":"奚关根"}],"doi":"10.3969/j.issn.1007-2780.2000.04.001","fpage":"243","id":"160f1a7c-1e65-44c6-8292-854c474ed731","issue":"4","journal":{"abbrevTitle":"YJYXS","coverImgSrc":"journal/img/cover/YJYXS.jpg","id":"72","issnPpub":"1007-2780","publisherId":"YJYXS","title":"液晶与显示   "},"keywords":[{"id":"9d8268c3-379f-4a6b-a83c-c3fb50e225c9","keyword":"液晶","originalKeyword":"液晶"},{"id":"7f8ffa03-0e58-4860-96ae-ee58f57b51d7","keyword":"中间体","originalKeyword":"中间体"},{"id":"ba246f11-f675-429c-af8b-6f99c2e85821","keyword":"合成","originalKeyword":"合成"}],"language":"zh","publisherId":"yjyxs200004001","title":"4-烷<span style=\"color:red\">氧基</span>联苯-4′-甲酸-(4-<span style=\"color:red\">羧基</span>)<span style=\"color:red\">苯</span>酯的合成","volume":"15","year":"2000"},{"abstractinfo":"以<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>酮为原料,经<span style=\"color:red\">二</span>氯亚砜氯化得到9,9-<span style=\"color:red\">二</span>氯<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>中间体,无需分离纯化,将其分别与邻甲酚和2,6-<span style=\"color:red\">二</span>甲基苯酚进行取代反应,制得2个含<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>结构的双酚化合物9,9-<span style=\"color:red\">二</span>(4-羟基-3-甲基<span style=\"color:red\">苯基</span>)咕<span style=\"color:red\">吨</span>和9,9-<span style=\"color:red\">二</span>(4-羟基-3,5-<span style=\"color:red\">二</span>甲基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>,产率分别为81.0％和80.5％.用FTIR、1H NMR、13C NMR和元素分析对其组成和结构进行了表征.该法具有操作简单、反应条件温和及收率高等优点.","authors":[{"authorName":"付桂云","id":"93d37706-c65e-4374-a1ee-fe45e0e34c10","originalAuthorName":"付桂云"},{"authorName":"易飞","id":"babab2b1-d832-4fe2-929b-b2e6574d3969","originalAuthorName":"易飞"},{"authorName":"盛寿日","id":"033afec3-6d3e-44f5-ad98-fa45d54dde77","originalAuthorName":"盛寿日"},{"authorName":"曹伟","id":"80786533-8d6b-4312-939a-0a74735cc0aa","originalAuthorName":"曹伟"},{"authorName":"刘晓玲","id":"904bf1a8-2471-4f27-9975-c407725d4f58","originalAuthorName":"刘晓玲"}],"doi":"10.3724/SP.J.1095.2011.00549","fpage":"974","id":"729ad1e4-00cc-45af-b0c0-435551233ba8","issue":"8","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"452dc8cc-6b13-437e-81fb-7e99cb66490f","keyword":"咕<span style=\"color:red\">吨</span>酮","originalKeyword":"咕吨酮"},{"id":"99d24110-faca-424e-bb7a-26189149fe4b","keyword":"<span style=\"color:red\">二</span>氯<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>","originalKeyword":"二氯呫吨"},{"id":"5bec74c0-e1fe-4225-9d50-a22f4624d09e","keyword":"甲基苯酚","originalKeyword":"甲基苯酚"},{"id":"3e417890-8246-4809-bf1f-7d3be607a0d2","keyword":"<span style=\"color:red\">二</span>(羟基甲基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>","originalKeyword":"二(羟基甲基苯基)呫吨"},{"id":"6cdbad49-84f2-42c6-9086-2b4cfda2c51d","keyword":"<span style=\"color:red\">二</span>(羟基<span style=\"color:red\">二</span>甲基<span style=\"color:red\">苯基</span>)<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>","originalKeyword":"二(羟基二甲基苯基)呫吨"},{"id":"a05ede76-82d0-4a20-9e2c-7d72dcc70e5d","keyword":"合成","originalKeyword":"合成"}],"language":"zh","publisherId":"yyhx201108021","title":"2个含咕<span style=\"color:red\">吨</span>结构双酚化合物的合成","volume":"28","year":"2011"},{"abstractinfo":"以邻碘苯甲酸和8-羟基喹啉为原料,通过Ullmann反应合成了<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>酮并吡啶(2),再将其进行季铵化反应合成了它的甲基及乙基季铵盐化合物3a和3b,用IR、NMR、MS及元素分析等测试技术对其结构进行了表征. 运用四甲基偶氮唑盐微量酸反应比色法(MTT法)测得化合物3a和3b对体外培养人卵巢癌(A2780)、宫颈癌(Hela)、肺癌(SPC-A)和口腔上皮癌(KB)细胞的抑制作用均优于阳性对照药5-氟尿嘧啶(5-Fu). 溴乙锭置换荧光探针法测得化合物3a和3b与小牛胸腺DNA(CT-DNA)的表观结合常数分别为3.91×105和2.72×105 L/mol,揭示目标化合物的抗癌活性可能与其跟DNA的相互作用有关. 化合物3a和3b对乙酰胆碱酯酶(AChE)和丁酰胆碱酯酶(BuChE)均具有良好的选择性抑制活性,IC50值达μmol/L以下,与阳性对照药氢溴酸加兰他敏(Galantamine·HBr)近似,它们对AChE的抑制作用为非竞争性抑制.","authors":[{"authorName":"覃江克","id":"eb990228-b009-4759-821c-cbcabd759612","originalAuthorName":"覃江克"},{"authorName":"兰文丽","id":"cc1a9619-0101-498c-aa1b-28e366ecb81d","originalAuthorName":"兰文丽"},{"authorName":"韩留玉","id":"021c79f8-62d7-488a-b45c-94aa0598dc95","originalAuthorName":"韩留玉"},{"authorName":"唐煌","id":"75d79faf-1516-4465-8ce8-f826b4f1cbd2","originalAuthorName":"唐煌"},{"authorName":"苏桂发","id":"a337e0b4-ee78-41f4-a91a-541c68f12612","originalAuthorName":"苏桂发"},{"authorName":"戴支凯","id":"f71e1835-956f-4f1b-8d52-2175fed815a1","originalAuthorName":"戴支凯"},{"authorName":"徐庆","id":"ff84ee77-04b0-4f3b-b7f9-da62219c89cc","originalAuthorName":"徐庆"}],"doi":"10.3724/SP.J.1095.2010.90520","fpage":"528","id":"3195919b-198b-44ad-812c-46096819f16b","issue":"5","journal":{"abbrevTitle":"YYHX","coverImgSrc":"journal/img/cover/YYHX.jpg","id":"73","issnPpub":"1000-0518","publisherId":"YYHX","title":"应用化学"},"keywords":[{"id":"f2a6ab93-c248-4326-9ab1-b1810a93abc9","keyword":"<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>酮并吡啶","originalKeyword":"呫吨酮并吡啶"},{"id":"96cacfd8-844a-4f53-9105-7f9cd2b58996","keyword":"季铵盐","originalKeyword":"季铵盐"},{"id":"00179900-f10c-4e2a-ae3b-2ad734d7c405","keyword":"合成","originalKeyword":"合成"},{"id":"49f3aaae-a3d1-45dd-b0e5-096d70d72d60","keyword":"胆碱酯酶","originalKeyword":"胆碱酯酶"},{"id":"18711a92-15f6-4587-94e1-d18eafbf18d4","keyword":"抗癌","originalKeyword":"抗癌"},{"id":"596d5a27-5089-4acb-affb-90ccf6e17aba","keyword":"DNA","originalKeyword":"DNA"}],"language":"zh","publisherId":"yyhx201005007","title":"<span style=\"color:red\">呫</span><span style=\"color:red\">吨</span>酮并吡啶季铵盐的合成及其生物活性","volume":"27","year":"2010"},{"abstractinfo":"用三丁基乙基硫酸乙酯铵作相转移催化剂,以<span style=\"color:red\">苯</span><span style=\"color:red\">二</span>酚、一氯乙酸和氢氧化钠为原料,用三氯甲烷作溶剂,合成了3种不同结构的<span style=\"color:red\">苯</span><span style=\"color:red\">二氧基</span><span style=\"color:red\">二</span>乙酸.分别以油酸钠、十二胺和丁黄药为浮选捕收剂,考察了<span style=\"color:red\">苯</span><span style=\"color:red\">二氧基</span><span style=\"color:red\">二</span>乙酸对方解石、一水硬铝石和黄铁矿的抑制性能.结果表明,<span style=\"color:red\">苯</span><span style=\"color:red\">二氧基</span><span style=\"color:red\">二</span>乙酸的抑制能力较强,对上述3种矿物的抑制性能大小顺序为:方解石＞一水硬铝石＞黄铁矿,可作为方解石等含钙、镁脉石矿物的有效抑制剂.从基团电负性、浮选剂特性指数和亲憎平衡值等方面,对<span style=\"color:red\">苯</span><span style=\"color:red\">二氧基</span><span style=\"color:red\">二</span>乙酸的抑制性能进行了讨论.用MINDO 3方法对3种药剂进行了量化计算,量化计算结果表明,它们的抑制能力大小顺序为:对位＞间位＞邻位;它们均以负一价离子的形式与矿物中的金属离子发生作用,未离解的<span style=\"color:red\">羧基</span>则难以发生离解,从而保证药剂与矿物作用后的亲水性,使矿物得到抑制.","authors":[{"authorName":"张剑锋","id":"699abd99-5112-4530-b19b-e410a7f56330","originalAuthorName":"张剑锋"},{"authorName":"胡岳华","id":"76643a08-0109-4c29-9bc9-044af85164e1","originalAuthorName":"胡岳华"},{"authorName":"王淀佐","id":"9af673c2-d435-4b1e-93f5-51063b650515","originalAuthorName":"王淀佐"}],"doi":"","fpage":"707","id":"64609612-cad6-4a01-b383-387b97fde65f","issue":"4","journal":{"abbrevTitle":"ZGYSJSXB","coverImgSrc":"journal/img/cover/ZGYSJSXB.jpg","id":"88","issnPpub":"1004-0609","publisherId":"ZGYSJSXB","title":"中国有色金属学报"},"keywords":[{"id":"020a9e94-cf95-48cc-a1f9-a3f7faa032ff","keyword":"<span style=\"color:red\">苯</span><span style=\"color:red\">二氧基</span><span style=\"color:red\">二</span>乙酸","originalKeyword":"苯二氧基二乙酸"},{"id":"e32bd5ca-cc46-4da6-9a19-f71f9e73b9d2","keyword":"相转移催化","originalKeyword":"相转移催化"},{"id":"3eaa6c55-1877-4676-897f-7bbdc7793998","keyword":"浮选性能","originalKeyword":"浮选性能"},{"id":"6ada4a9c-4b81-4560-b5a6-9d212f7c3fe2","keyword":"抑制","originalKeyword":"抑制"}],"language":"zh","publisherId":"zgysjsxb200104036","title":"<span style=\"color:red\">苯</span><span style=\"color:red\">二氧基</span><span style=\"color:red\">二</span>乙酸的相转移催化合成及其浮选性能","volume":"11","year":"2001"}],"totalpage":3350,"totalrecord":33494}