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Application of Amino-Functionalized SBA-15 Type Mesoporous Silica in One-Pot Synthesis of Spirooxindoles

Ghodsi MOHAMMADI ZIARANI , Alireza BADIEI , Somayeh MOUSAVI , Negar LASHGARI , Afsaneh SHAHBAZI

催化学报 doi:10.1016/S1872-2067(11)60456-7

Amino-functionalized SBA-15(SBA-Pr-NH2) has been used as a new basic nanocatalyst in the one-pot synthesis of spirooxindole derivatives via the three-component condensation reaction of isatins, activated methylene reagents, and dimedone in an aqueous medium. SBA-Pr-NH2 has been established as an efficient heterogeneous nanoporous solid basic catalyst (pore size of 6 nm) that can be easily handled and removed from the reaction mixture by simple filtration, and also recovered and reused without noticeable loss of reactivity.

关键词: amino-functionalized SBA-15 , spirooxindoles , isatin , nano-reactor , green synthesis

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